Christina Applegate on Being Diagnosed with MS, Martin Short Rivalry with Jimmy & Going to Coachella

Christina talks about having a very sick sense of humor, being diagnosed with MS in 2021, starting the podcast MeSsy with her friend Jamie-Lynn Sigler, her friendship with Martin Short, Marty reveals whether he likes Christina or Jimmy more, “audio descriptions” on reality shows, going to Coachella with her daughter, and Jimmy shows a great clip from 1981 of Christina in the movie Jaws of Satan as a nine-year-old.

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Jimmy Kimmel serves as host and executive producer of Emmy®-nominated “Jimmy Kimmel Live!,” ABC’s late-night talk show. “Jimmy Kimmel Live!” is well known for its huge viral video successes, with over 15 billion views and more than 18 million subscribers on the show’s YouTube channel. Some of Kimmel’s most popular comedy bits include “Celebrities Read Mean Tweets,” “Lie Witness News,” “Unnecessary Censorship,” “Halloween Candy YouTube Challenge,” and music videos like “I (Wanna) Channing All Over Your Tatum.”